MHI

Introduction

Course 207: Study Guide

Module 1: Fundamentals of Hydrogen Inhalation

1.1 The Relationship Between Inhaled H2 and Cellular H2 Concentration

1.1.1 Atmospheric Gas Composition and Henry’s Law

1.1.2 H2 Inhalation and Cellular Concentration

1.1.3 Common Misunderstandings about H2 Inhalation

1.1 Quiz

1.2 Fraction of Inspired H2 (FiH2): A Standardized Measure

1.2.1 Defining Fraction of Inspired H2 (FiH2)

1.2.2 How FiH2 Varies with Delivery Methods (e.g., Nasal Cannulas)

1.2 Quiz

1.3 Factors Influencing FiH2: Breathing Patterns and Flow Rates

1.3.1 Practical ventilation rates

1.3.2 Interpretation of practical ventilation for FiH2

1.3.3 Example Flow Rate Estimates

1.3.4 Inhalation Patterns and Variability

1.3 Quiz

1.4 FiH2 and H2 Flow Rates

1.4 Quiz

Module 2: Recommended Inhalation Parameters

2.1 Understanding dose for H2 inhalation

2.1 Quiz

2.2 Minimum cellular concentration and FiH2

2.2 Quiz

2.3 Minimum Duration of H2 Cellular Exposure

2.3 Quiz

2.4 Minimum recommended H2 flow rate for minimum FiH2

2.4 Quiz

2.5 Optimal and Maximum Concentration/Flow Rate Recommendations

2.5.1 Maximal and optimal H2 concentrations

2.5.2 Maximal and optimal flow rates

2.5 Quiz

2.6 Minimum, Maximum, and Optimal Duration and Frequency of H2 Inhalation

2.6 Quiz

3.1 Estimating FiH2 via Inspiratory Flow Rate

3.1 Quiz

3.2 Calculating Administered Concentration and Dose

3.2.1 FiH2 Example Calculations

3.2 Quiz

3.3 How To Measure H2 Flow Rate

3.3 Quiz

Module 4 Oxyhydrogen (Brown’s Gas): Comparisons And Considerations

4.1 Differences Between Oxyhydrogen And Pure Hydrogen

4.1 Quiz

4.2 Confounding Variables In Cell Culture Studies

4.2 Quiz

4.3 Is Oxyhydrogen Superior To Pure Hydrogen?

4.3.1 Potential Added Benefits of Oxyhydrogen

4.3.2 The Unnecessary Need For Extra Oxygen In Individuals Without Impaired Lung Function

4.3.3 Potential Harmful Effects Of Oxyhydrogen

4.3 Quiz

4.4 Is Pure H2 Superior To Oxyhydrogen?

4.4.1 Hypoxia as a Therapeutic Concept

4.4.2 Does Less Oxygen Offer an Advantage?

4.4 Quiz

4.5 Oxyhydrogen Summary

5.1 Flammability Concerns With Hydrogen Inhalation

5.1 Quiz

5.2 Flow Rates And Flammability Risks

5.2.1 Balancing Therapeutic Efficacy and Safety

5.2.2 Exhalation Dynamics and Safe Limits

5.2.3 Final Safety Recommendations To Mitigate Flammability Risk

5.2 Quiz

5.3 Ensuring Gas Purity: Potential Hazards Of Contaminants And Electrolytes

5.3 Quiz